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SB-756050 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750112

MBS5750112 is an inhibitor targeting SB-756050. More details

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Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SB-756050, Inhibitor
Full Product Name
SB-756050
Product Gene Name
SB-756050, inhibitor
Form/Format
POWDER
Purity/Purification
99.5%
Preparation and Storage
For 3 years at -20 degree C (powder)
For 2 years -80 degree C in solvent.
Molecular Weight
500.59
CAS
447410-57-3
Formula
C21H28N2O8S2
Pathways
GPCR/G Protein
Smiles
O=S(=O)(N1CCN(S(=O)(=O)c2ccc(OC)c(OC)c2)CCC1)c1ccc(OC)c(OC)c1
Receptor
TGR5
Bioactivity
SB756050 is a selective TGR5 agonist currently in phase 1clinical trials for the treatment of type 2 diabetes.
Solubility Note
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Structure of SB-756050, inhibitor

SB-756050 Inhibitor – Cat# MBS5750112

Product References and Citations for SB-756050, inhibitor

1. Hodge RJ, et al. Safety, Pharmacokinetics, and Pharmacodynamic Effects of a Selective TGR5 Agonist, SB-756050, in Type 2 Diabetes. Clin Pharmacol Drug Dev. 2013 Jul; 2 (3):213-22.

Other Notes

Small volumes of SB-756050, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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