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AZD4635 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750415

MBS5750415 is an inhibitor targeting AZD4635. AZD4635 is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AZD4635, Inhibitor
Full Product Name
AZD4635
Product Gene Name
AZD4635, inhibitor
Product Synonym Names
Adenosine Receptor
Form/Format
POWDER
Purity/Purification
99.1%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
315.74
CAS Number
1321514-06-0
Formula
C15H11ClFN5
Smiles
CC1=NC(=CC(=C1)C2=C(N=C(N=N2)N)C3=CC=C(C=C3)F)Cl
Solubility
DMSO: Soluble
Pathways
GPCR; G Protein
Receptor
A2A
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for AZD4635, inhibitor

Cancer

Chemical Structure of AZD4635, inhibitor

AZD4635 Inhibitor – Cat# MBS5750415

Product References and Citations for AZD4635, inhibitor

1. Alexandra Borodovsky, et al. Abstract 5580: PreClinicalal pharmacodynamics and antitumor activity of AZD4635, a novel adenosine 2A receptor inhibitor that reverses adenosine mediated T cell suppression. AACR; Cancer Res 2017; 77(13 Suppl):Abstract nr 5580.

Other Notes

Small volumes of AZD4635, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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