AM966 Inhibitor

Name: AM966 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5750426
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750426

AM966, a excellent affinity, specific, oral LPA1(IC50=17 nM) antagonist, suppresses LPA-stimulated intracellular calcium release. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AM966, Inhibitor

Full Product Name

AM966

Product Gene Name

AM966, inhibitor

Product Synonym Names

LPA Receptor

Form/Format

POWDER

Purity/Purification

99.5%

Preparation and Storage

Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C

Molecular Weight

490.94

CAS Number

1228690-19-4

Formula

C27H23ClN2O5

Smiles

O=C(O)CC(C=C1)=CC=C1C(C=C2)=CC=C2C3=C(NC(O[C@H](C)C4=C(Cl)C=CC=C4)=O)C(C)=NO3

Solubility

DMSO: >=105 mg/mL

Pathways

GPCR; G Protein

Receptor

LPA1

Product Remark

For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for AM966, inhibitor

Cancer

Product References and Citations for AM966, inhibitor

1. Swaney, JS, et al. A novel, orally active LPA1 receptor antagonist inhibits lung fibrosis in the mouse bleomycin model. Br J Pharmacol. 2010 Aug; 160(7):1699-713.

Other Notes

Small volumes of AM966, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AM966 purchase

MBS5750426 is an inhibitor targeting AM966.