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AD80 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750442

AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AD80, Inhibitor
Full Product Name
AD80
Product Gene Name
AD80, inhibitor
Product Synonym Names
c-RET; Raf; Src; S6 Kinase
Form/Format
POWDER
Purity/Purification
100.0%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
473.44
CAS Number
1384071-99-1
Formula
C22H19F4N7O
Smiles
CC(C)N1C2=C(C(=N1)C3=CC=C(C=C3)NC(=O)NC4=C(C=CC(=C4)C(F)(F)F)F)C(=NC=N2)N
Solubility
DMSO: >=150 mg/mL
Pathways
Tyrosine Kinase; Adaptors; MAPK; Angiogenesis; PI3K; Akt; mTOR Signaling
Receptor
RET, RAF, SRC, S6K
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of AD80, inhibitor

AD80 Inhibitor – Cat# MBS5750442

Product References and Citations for AD80, inhibitor

1. Dar AC, et al. Chemical genetic discovery of targets and anti-targets for cancer polypharmacology.Nature. 2012 Jun 6; 486(7401):80-4.

Other Notes

Small volumes of AD80, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AD80 purchase

MBS5750442 is an inhibitor targeting AD80.
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