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PF-06840003 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750448

MBS5750448 is an inhibitor targeting PF-06840003. PF-06840003 is a specific and oral active IDO-1 inhibitor. More details

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Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PF-06840003, Inhibitor
Full Product Name
PF-06840003
Product Gene Name
PF-06840003, inhibitor
Product Synonym Names
IDO
Form/Format
POWDER
Purity/Purification
99.9%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
232.21
CAS Number
198474-05-4
Formula
C12H9FN2O2
Smiles
O=C(C(C1=CNC2=C1C=C(F)C=C2)C3)NC3=O
Solubility
DMSO: >=28 mg/mL
Pathways
Metabolism
Receptor
IDO1
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for PF-06840003, inhibitor

Cancer

Chemical Structure of PF-06840003, inhibitor

PF-06840003 Inhibitor – Cat# MBS5750448

Product References and Citations for PF-06840003, inhibitor

1. Tumang J, et al. PF-06840003: a highly selective IDO-1 inhibitor that shows good in vivo efficacy in combination with immune checkpoint inhibitors. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016; 76(14 Suppl):Abstract nr4863.

Other Notes

Small volumes of PF-06840003, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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