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ML365 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750457

MBS5750457 is an inhibitor targeting ML365. ML365 is a novel selective small molecule inhibitor of TASK1(KCNK3). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ML365, Inhibitor
Full Product Name
ML365
Product Gene Name
ML365, inhibitor
Product Synonym Names
Potassium Channel
Form/Format
POWDER
Purity/Purification
99.9%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
360.41
CAS Number
947914-18-3
Formula
C22H20N2O3
Smiles
COc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1
Solubility
DMSO: 10 mM
Pathways
Membrane Transporter; Ion Channel
Receptor
TASK-1
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of ML365, inhibitor

ML365 Inhibitor – Cat# MBS5750457

Product References and Citations for ML365, inhibitor

1. Zou B, et al. ML365: Development of Bis-Amides as Selective Inhibitors of the KCNK3/TASK1 Two Pore Potassium Channel. Probe Reports from the NIH Molecular Libraries Program [Internet].

Other Notes

Small volumes of ML365, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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