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Flumatinib Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750459

Flumatinib is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity. More details

Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Flumatinib, Inhibitor
Full Product Name
Flumatinib
Product Synonym Names
Bcr-Abl; PDGFR; c-Kit
Form/Format
POWDER
Purity/Purification
100.0%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
562.6
CAS Number
895519-90-1
Formula
C29H29F3N8O
Smiles
CC1=C(C=C(C=N1)NC(=O)C2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5
Solubility
DMSO: >=32 mg/mL
Pathways
Angiogenesis; Tyrosine Kinase; Adaptors
Receptor
c-Abl; PDGFRbeta; c-Kit;
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for Flumatinib, inhibitor

Chemical Structure of Flumatinib, inhibitor

Flumatinib Inhibitor – Cat# MBS5750459

Product References and Citations for Flumatinib, inhibitor

1. Luo H, et al. HH-GV-678, a novel selective inhibitor of Bcr-Abl, outperforms imatinib and effectively overrides imatinib resistance. Leukemia. 2010 Oct; 24(10):1807-9.

Other Notes

Small volumes of Flumatinib, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Flumatinib purchase

MBS5750459 is an inhibitor targeting Flumatinib.
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