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Indisulam Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750460

Indisulam is a carbonic anhydrase inibitor and Antitumor CDK inhibitor. Indisulam targets the G1 phase of the cell cycle by depleting cyclin E. inducing p53 and p21, and inhibiting CDK2, causing a blockade in the G1/S transition. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Indisulam, Inhibitor
Full Product Name
Indisulam
Product Synonym Names
Carbonic Anhydrase; CDK
Form/Format
POWDER
Purity/Purification
98.7%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
385.85
CAS Number
165668-41-7
Formula
C14H12ClN3O4S2
Smiles
C1=CC2=C(C(=C1)NS(=O)(=O)C3=CC=C(C=C3)S(=O)(=O)N)NC=C2Cl
Solubility
DMSO: 20 mg/mL, Clear
Pathways
Metabolism; Cell Cycle; Checkpoint
Receptor
carbonic anhydrase; CDK
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of Indisulam, inhibitor

Indisulam Inhibitor – Cat# MBS5750460

Product References and Citations for Indisulam, inhibitor

1. Ozawa Y.et al.E7070, a novel sulphonamide agent with potent antitumour activity in vitro and in vivo.Eur J Cancer. 2001 Nov; 37(17):2275-82.

Other Notes

Small volumes of Indisulam, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Indisulam purchase

MBS5750460 is an inhibitor targeting Indisulam.
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