COTI-2 Inhibitor

Name: COTI-2 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5750463
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750463

COTI-2, an orally available thiosemicarbazone, is an activator of mutant forms of the p53 protein with potential antineoplastic activity. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

COTI-2, Inhibitor

Full Product Name

COTI-2

Product Gene Name

COTI-2, inhibitor

Product Synonym Names

p53

Form/Format

POWDER

Purity/Purification

99.0%

Preparation and Storage

Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C

Molecular Weight

366.49

CAS Number

1039455-84-9

Formula

C19H22N6S

Smiles

S=C(NN=C1CCCc2cccnc12)N1CCN(CC1)c1ccccn1

Solubility

DMSO: 10 mM

Pathways

Apoptosis

Receptor

p53 mutants

Product Remark

For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for COTI-2, inhibitor

Cancer

Product References and Citations for COTI-2, inhibitor

1. Bykov VJN,etal.Targeting mutant p53 for efficient cancer therapy.Nat Rev Cancer. 2018 Feb; 18(2):89-102.

Other Notes

Small volumes of COTI-2, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for COTI-2 purchase

MBS5750463 is an inhibitor targeting COTI-2.