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OSS_128167 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750465

OSS_128167 is a specific SIRT6 inhibitor, and for SIRT6(IC50=89 uM), SIRT1(IC50=1578 uM) and SIRT2(IC50=751 uM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
OSS_128167, Inhibitor
Full Product Name
OSS_128167
Product Gene Name
OSS_128167, inhibitor
Product Synonym Names
Sirtuin inhibitor
Form/Format
POWDER
Purity/Purification
99.3%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
366.33
CAS Number
887686-02-4
Formula
C19H14N2O6
Smiles
O=C(Nc1cc(ccc1)C(=O)Nc2cc(C(=O)O)c(O)cc2)c3ccco3
Solubility
DMSO: 68 mg/mL (185.6 mM); Ethanol: <1 mg/mL; Water: <1 mg/mL
Pathways
Chromatin; Epigenetic
Receptor
SIRT6; SIRT2; SIRT1
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of OSS_128167, inhibitor

OSS_128167 Inhibitor – Cat# MBS5750465

Product References and Citations for OSS_128167, inhibitor

1. Parenti MD, et al. Discovery of novel and selective SIRT6 inhibitors. J Med Chem. 2014 Jun 12; 57(11):4796-804.

Other Notes

Small volumes of OSS_128167, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OSS_128167 purchase

MBS5750465 is an inhibitor targeting OSS_128167.
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