EPZ020411 2HCl Inhibitor

Name: EPZ020411 2HCl Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5750470
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750470

EPZ020411 is an effective and specific small molecule PRMT6 inhibitor (IC50=10 nM). More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

EPZ020411 2HCl, Inhibitor

Full Product Name

EPZ020411 2HCl (1700663-41-7(Free Base))

Product Synonym Names

Histone Methyltransferase

Form/Format

POWDER

Purity/Purification

99.2%

Preparation and Storage

Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C

Molecular Weight

515.51

CAS Number

1700663-41-7 (Free Base)

Formula

C25H40Cl2N4O3

Smiles

Cl.Cl.CNCCN(C)Cc1c[nH]nc1-c1ccc(O[C@H]2C[C@@H](C2)OCCC2CCOCC2)cc1

Solubility

DMSO: 93 mg/mL (180.4 mM); Ethanol: 93 mg/mL (180.4 mM)

Pathways

Chromatin; Epigenetic

Receptor

PRMT6; PRMT1; PRMT8

Product Remark

For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for EPZ020411 2HCl, inhibitor

Cancer

Product References and Citations for EPZ020411 2HCl, inhibitor

1. Mitchell LH, et al. Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 ToolCompound. ACS Med Chem Lett. 2015 Apr 6; 6(6):655-659.

Other Notes

Small volumes of EPZ020411 2HCl, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EPZ020411 2HCl purchase

MBS5750470 is an inhibitor targeting EPZ020411 2HCl. Also known as EPZ020411 2HCl (1700663-41-7(Free Base)).