• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

YU238259 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750475

YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining (NHEJ), in cell-based GFP reporter assays. More details

Please Inquire
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
YU238259, Inhibitor
Full Product Name
YU238259
Product Gene Name
YU238259, inhibitor
Product Synonym Names
DNA-PK inhibitor
Form/Format
POWDER
Purity/Purification
99.4%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
459.95
CAS Number
1943733-16-1
Formula
C22H22ClN3O4S
Smiles
COc1ccc(cc1)S(=O)(=O)NCc2ccc(cc2)C(=O)NCCc3ccc(Cl)cn3
Solubility
DMSO: 84 mg/mL (182.6 mM); Ethanol: <1 mg/mL; Water: <1 mg/mL
Pathways
DNA Damage; DNA Repair
Receptor
HDR
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of YU238259, inhibitor

YU238259 Inhibitor – Cat# MBS5750475

Product References and Citations for YU238259, inhibitor

Stachelek GC,etal.YU238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-Deficient Tumors.Mol Cancer Res. 2015 Oct; 13(10):1389-97.

Other Notes

Small volumes of YU238259, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for YU238259 purchase

MBS5750475 is an inhibitor targeting YU238259.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000