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Syk Inhibitor II

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750483

Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Syk Inhibitor II, Inhibitor
Full Product Name
Syk Inhibitor II
Product Synonym Names
Syk inhibitor
Form/Format
POWDER
Purity/Purification
98.0%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
340.3
CAS Number
726695-51-8
Formula
C14H15F3N6O
Smiles
NCCNC1=NC(NC2=CC(C(F)(F)F)=CC=C2)=C(C(N)=O)C=N1
Solubility
Water: 25 mg/mL; DMSO: 100 mg/mL
Pathways
Angiogenesis
Receptor
Syk
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of Syk Inhibitor II, inhibitor

Syk Inhibitor II – Cat# MBS5750483

Product References and Citations for Syk Inhibitor II, inhibitor

1. Hisamichi H,etal.Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives.Bioorg Med Chem. 2005 Aug 15; 13(16):4936-51.

Other Notes

Small volumes of Syk Inhibitor II, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Syk Inhibitor II purchase

MBS5750483 is an inhibitor targeting Syk Inhibitor II.
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