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Nampt-IN-1 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750504

Nampt-IN-1 (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Nampt-IN-1, Inhibitor
Full Product Name
Nampt-IN-1
Product Synonym Names
NAMPT; CSF-1R
Form/Format
POWDER
Purity/Purification
99.4%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
419.49
CAS Number
1698878-14-6
Formula
C20H25N3O5S
Smiles
CC(C)(O)CS(=O)(=O)Nc1ccc2CN(CCc2c1)C(=O)COc3cccnc3
Solubility
DMSO: >=30 mg/mL
Pathways
Metabolism; Tyrosine Kinase; Adaptors
Receptor
NAMPT; CSF-1R
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of Nampt-IN-1, inhibitor

Nampt-IN-1 Inhibitor – Cat# MBS5750504

Product References and Citations for Nampt-IN-1, inhibitor

1. Zhao G, et al. Discovery of a Highly Selective NAMPT Inhibitor That Demonstrates Robust Efficacy and Improved Retinal Toxicity with Nicotinic Acid Coadministration. Mol Cancer Ther. 2017 Dec; 16(12):2677-2688.

Other Notes

Small volumes of Nampt-IN-1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Nampt-IN-1 purchase

MBS5750504 is an inhibitor targeting Nampt-IN-1.
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