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MS049 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750506

MS 049 is a potent, selective, and cell-active dual inhibitor of PRMT4 and PRMT6 with IC 50 of 34 nM and 43 nM, respectively. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MS049, Inhibitor
Full Product Name
MS049
Product Gene Name
MS049, inhibitor
Product Synonym Names
Histone Methyltransferase inhibitor
Form/Format
POWDER
Purity/Purification
98.0%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
248.36
CAS Number
1502816-23-0
Formula
C15H24N2O
Smiles
CNCCN1CCC(CC1)OCc2ccccc2
Solubility
DMSO: >=31 mg/mL
Pathways
Chromatin; Epigenetic
Receptor
PRMT4; PRMT6
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of MS049, inhibitor

MS049 Inhibitor – Cat# MBS5750506

Product References and Citations for MS049, inhibitor

1. Shen Y,etal.Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6.J Med Chem. 2016 Oct 13; 59(19):9124-9139.

Other Notes

Small volumes of MS049, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MS049 purchase

MBS5750506 is an inhibitor targeting MS049.
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