• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

PF-4840154 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750512

PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel and elicited TrpA1-mediated nocifensive behaviour in mouse, with EC50 of 97 nM and 23 nM for rTrpA1 and hTrpA1, respectively. More details

Please Inquire
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PF-4840154, Inhibitor
Full Product Name
PF-4840154
Product Gene Name
PF-4840154, inhibitor
Product Synonym Names
TRP/TRPV Channel
Form/Format
POWDER
Purity/Purification
98.0%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
466.63
CAS Number
1332708-14-1
Formula
C26H38N6O2
Smiles
CC(C)CNc2nc(ncc2C(=O)NCc1ccccc1)N3CCN(CC3)CC4CCCOC4
Solubility
DMSO: 4.66 mg/mL (10 mM)
Pathways
Membrane Transporter; Ion Channel
Receptor
rTRPA1; hTRPA1
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of PF-4840154, inhibitor

PF-4840154 Inhibitor – Cat# MBS5750512

Product References and Citations for PF-4840154, inhibitor

1. Ryckmans T,etal.Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel.Bioorg Med Chem Lett. 2011 Aug 15; 21(16):4857-9.

Other Notes

Small volumes of PF-4840154, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PF-4840154 purchase

MBS5750512 is an inhibitor targeting PF-4840154.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000