LX2343 Inhibitor

Name: LX2343 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5750523
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750523

LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43+/-0.36 uM. LX2343 acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99+/-3.23 uM. LX2343 stimulates autophagy in its promotion of Abeta clearance. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LX2343, Inhibitor

Full Product Name

LX2343

Product Gene Name

LX2343, inhibitor

Product Synonym Names

BACE

Form/Format

POWDER

Purity/Purification

99.9%

Preparation and Storage

Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C

Molecular Weight

474.91

CAS Number

333745-53-2

Formula

C22H19ClN2O6S

Smiles

Clc1cc(c(OC)cc1)N(CC(=O)Nc2ccc3OCOc3c2)S(=O)(=O)c4ccccc4

Solubility

DMSO: >=155 mg/mL

Pathways

Neuroscience

Receptor

BACE1

Product Remark

For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for LX2343, inhibitor

Neurological Disease

Product References and Citations for LX2343, inhibitor

1. Guo XD,etal.Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid beta production and clearance.Acta Pharmacol Sin. 2016 Sep; 37(10):1281-1297.

Other Notes

Small volumes of LX2343, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LX2343 purchase

MBS5750523 is an inhibitor targeting LX2343.