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DIM-C-pPhOH Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750525

Nur77 (NR4A1) antagonist. Inhibits TGF-beta induced cell migration of breast cancer cell lines. Promotes ROS/endoplasmic reticulum stress and proapoptotic pathways in pancreatic cancer cell lines. Mimics effects of Nur77 RNAi silencing. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DIM-C-pPhOH, Inhibitor
Full Product Name
DIM-C-pPhOH
Product Gene Name
DIM-C-pPhOH, inhibitor
Product Synonym Names
Nur 77 antagonist
Form/Format
POWDER
Purity/Purification
99.8%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
338.41
CAS Number
151358-47-3
Formula
C23H18N2O
Smiles
Oc1ccc(cc1)C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Solubility
DMSO: 33.84 mg/mL(100mM); Ethanol: 33.84 mg/mL(100mM)
Pathways
NF-kappaB
Receptor
Nur77
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for DIM-C-pPhOH, inhibitor

Cell Cycle and Inflammation

Chemical Structure of DIM-C-pPhOH, inhibitor

DIM-C-pPhOH Inhibitor – Cat# MBS5750525

Product References and Citations for DIM-C-pPhOH, inhibitor

1. Chintharlapalli S,etal.Activation of Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways.J Biol Chem. 2005 Jul 1; 280(26):24903-14.

Other Notes

Small volumes of DIM-C-pPhOH, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DIM-C-pPhOH purchase

MBS5750525 is an inhibitor targeting DIM-C-pPhOH.
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