LM10 Inhibitor

Name: LM10 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5750531
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750531

Selective tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 uM for human and mouse TDO, respectively). Exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. Reduces growth of TDO-expressing P815… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LM10, Inhibitor

Full Product Name

LM10

Product Gene Name

LM10, inhibitor

Product Synonym Names

TDO inhibitor

Form/Format

POWDER

Purity/Purification

99.9%

Preparation and Storage

Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C

Molecular Weight

229.22

CAS Number

1316695-35-8

Formula

C11H8FN5

Smiles

Fc1ccc2c(\C=C\c3nnn[nH]3)c[nH]c2c1

Solubility

DMSO: 22.92 mg/mL(100 mM); Ethanol: 4.58 mg/mL(20 mM)

Pathways

Metabolism

Receptor

TDO

Product Remark

For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for LM10, inhibitor

Metabolic Disease

Product References and Citations for LM10, inhibitor

1. Pilotte L,etal.Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase.Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7):2497-502.

Other Notes

Small volumes of LM10, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LM10 purchase

MBS5750531 is an inhibitor targeting LM10.