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LDC-4297 HCl Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750536

MBS5750536 is an inhibitor targeting LDC-4297 HCl. Also known as LDC-4297 HCl (1453834-21-3(Free Base)). LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LDC-4297 HCl, Inhibitor
Full Product Name
LDC-4297 HCl (1453834-21-3(Free Base))
Product Synonym Names
CDK
Form/Format
POWDER
Purity/Purification
99.8%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
469.02
CAS Number
1453834-21-3 (Free Base)
Formula
C23H29ClN8O
Smiles
Cl.CC(C)c1cnn2c(NCc3ccccc3-n3cccn3)nc(OC3CCCNC3)nc12
Solubility
DMSO: >=60 mg/mL
Pathways
Cell Cycle; Checkpoint
Receptor
CDK7
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of LDC-4297 HCl, inhibitor

LDC-4297 HCl Inhibitor – Cat# MBS5750536

Product References and Citations for LDC-4297 HCl, inhibitor

1. Hutterer C,etal. A novel CDK7 inhibitor of the Pyrazolotriazine class exerts broad-spectrum antiviral activity at nanomolar concentrations.Antimicrob Agents Chemother. 2015 Apr; 59(4):2062-71.

Other Notes

Small volumes of LDC-4297 HCl, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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