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SLV-2436 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750542

SLV-2436 (SEL201) is a novel effective and ATP-competitive inhibitor of MNK1 and MNK2 (IC50: 10.8/5.4?nM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SLV-2436, Inhibitor
Full Product Name
SLV-2436
Product Gene Name
SLV-2436, inhibitor
Product Synonym Names
MNK
Form/Format
POWDER
Purity/Purification
99.9%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
349.79
CAS Number
2095704-43-9
Formula
C19H14ClN4O
Smiles
Nc1n[nH]c2cc(ccc12)-c1ccc(=O)n(Cc2cccc(Cl)c2)c1
Solubility
DMSO: 10 mM
Pathways
MAPK
Receptor
MNK1; MNK2
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of SLV-2436, inhibitor

SLV-2436 Inhibitor – Cat# MBS5750542

Product References and Citations for SLV-2436, inhibitor

1. Zhan Y, Guo J, Yang W, et al. MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma.[J]. Journal of Clinical Investigation, 2017, 127(11):4179.

Other Notes

Small volumes of SLV-2436, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SLV-2436 purchase

MBS5750542 is an inhibitor targeting SLV-2436.
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