CEP-40783 Inhibitor

Name: CEP-40783 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5750543
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750543

CEP-40783 is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM). More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CEP-40783, Inhibitor

Full Product Name

CEP-40783

Product Gene Name

CEP-40783, inhibitor

Product Synonym Names

TAM Receptor

Form/Format

POWDER

Purity/Purification

98.0%

Preparation and Storage

Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C

Molecular Weight

588.56

CAS Number

1437321-24-8

Formula

C31H26F2N4O6

Smiles

COc1cc2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c2cc1OC

Solubility

DMSO: 10 mg/mL; Ethanol: 2 mg/mL; Water: Insoluble

Pathways

Tyrosine Kinase; Adaptors

Receptor

AXL; Mer; Tyro3

Product Remark

For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for CEP-40783, inhibitor

Cancer

Product References and Citations for CEP-40783, inhibitor

1. Miknyoczki S, Cheng M, Hudkins R, et al. Abstract C275: CEP-40783: A potent and selective AXL/c-Met inhibitor for use in breast, non-small cell lung (NSCLC), and pancreatic cancers.[J]. Molecular Cancer Therapeutics, 2013, 12(11_Supplement):C275-C275.

Other Notes

Small volumes of CEP-40783, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CEP-40783 purchase

MBS5750543 is an inhibitor targeting CEP-40783.