Tirapazamine Inhibitor

Name: Tirapazamine Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5750549
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750549

Tirapazamine is a potent cytotoxic agent under hypoxic conditions, can induce apoptosis by inducing breaks in single and double-stranded DNA, as well as chromosomal breaks. The compound sensitizes cells to other ionizing radiation and other cytotoxic agents… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Tirapazamine, Inhibitor

Full Product Name

Tirapazamine

Form/Format

POWDER

Purity/Purification

99.87%

Preparation and Storage

Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C

Molecular Weight

178.15

CAS Number

27314-97-2

Formula

C7H6N4O2

Smiles

Nc1n[n+]([O-])c2ccccc2[n+]1[O-]

Solubility

DMSO: >10 mg/mL

Product Remark

For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for Tirapazamine, inhibitor

Cancer

Product References and Citations for Tirapazamine, inhibitor

1. Cai T Y, Liu X W, Zhu H, et al. Tirapazamine sensitizes hepatocellular carcinoma cells to topoisomerase I inhibitors via cooperative modulation of hypoxia-inducible factor-1alpha[J]. Molecular cancer therapeutics, 2013: molcanther. 0490.2013.

Other Notes

Small volumes of Tirapazamine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tirapazamine purchase

MBS5750549 is an inhibitor targeting Tirapazamine.