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RO1138452 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750551

RO1138452 is a selective and orally bioavailable antagonist of prostacyclin receptor (pKi: 8.3). It antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cyclic AMP accumulation in a dose-dependent manner.… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RO1138452, Inhibitor
Full Product Name
RO1138452
Form/Format
POWDER
Purity/Purification
98.0%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
309.41
CAS Number
221529-58-4
Formula
C19H23N3O
Smiles
CC(C)Oc1ccc(Cc2ccc(NC3=NCCN3)cc2)cc1
Solubility
DMSO: 100 mM; Water: 100 mM
Receptor
Prostacyclin Receptor
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of RO1138452, inhibitor

RO1138452 Inhibitor – Cat# MBS5750551

Product References and Citations for RO1138452, inhibitor

1. Clark R D, Jahangir A, Severance D, et al. Discovery and SAR development of 2-(phenylamino) imidazolines as postacyclin receptor antagonists[J]. Bioorganic & medicinal chemistry letters, 2004, 14(4): 1053-1056.

Other Notes

Small volumes of RO1138452, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RO1138452 purchase

MBS5750551 is an inhibitor targeting RO1138452.
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