AZ32 Inhibitor

Name: AZ32 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5750557
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750557

AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AZ32, Inhibitor

Full Product Name

AZ32

Product Gene Name

AZ32, inhibitor

Product Synonym Names

ATM/ATR

Form/Format

POWDER

Purity/Purification

98.00%

Preparation and Storage

Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C

Molecular Weight

328.37

Formula

C20H16N4O

Smiles

CNC(=O)c1ccc(cc1)-c1cnc2cnc(cn12)-c1ccccc1

Solubility

DMSO: >=150 mg/mL

Pathways

DNA Damage; DNA Repair

Receptor

ATM; ATM (in cell)

Product Remark

For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for AZ32, inhibitor

Cancer

Product References and Citations for AZ32, inhibitor

1. Karlin J, et al. Orally Bioavailable and Blood-Brain Barrier-Penetrating ATM Inhibitor (AZ32) Radiosensitizes Intracranial Gliomas in Mice. Mol Cancer Ther. 2018 Aug; 17(8):1637-1647.

Other Notes

Small volumes of AZ32, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZ32 purchase

MBS5750557 is an inhibitor targeting AZ32.