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Roflumilast N-oxide Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750574

MBS5750574 is an inhibitor targeting Roflumilast N-oxide. Roflumilast N-oxide is a PDE type 4 inhibitor. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Roflumilast N-oxide, Inhibitor
Full Product Name
Roflumilast N-oxide
Product Synonym Names
Phosphodiesterase (PDE)
Form/Format
POWDER
Purity/Purification
98.00%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
419.21
CAS Number
292135-78-5
Formula
C17H14Cl2F2N2O4
Smiles
[O-][n+]1cc(Cl)c(NC(=O)c2ccc(OC(F)F)c(OCC3CC3)c2)c(Cl)c1
Solubility
DMSO: 320 mg/mL
Pathways
Metabolism
Receptor
PDE4
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of Roflumilast N-oxide, inhibitor

Roflumilast N-oxide Inhibitor – Cat# MBS5750574

Product References and Citations for Roflumilast N-oxide, inhibitor

1. Victoni T,etal.Roflumilast n-oxide associated with PGE2 prevents the neutrophil elastase-induced production of chemokines by epithelial cells.Int Immunopharmacol. 2016 Jan; 30:1-8.

Other Notes

Small volumes of Roflumilast N-oxide, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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