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Rucaparib Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750575

Rucaparib is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, and also shows binding affinity to eight other PARP. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Rucaparib, Inhibitor
Full Product Name
Rucaparib
Product Synonym Names
PARP
Form/Format
POWDER
Purity/Purification
99.89%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
323.36
CAS Number
283173-50-2
Formula
C19H18FN3O
Smiles
CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23
Solubility
DMSO: 10 mM
Pathways
DNA Damage; DNA Repair; Chromatin; Epigenetic
Receptor
PARP1
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of Rucaparib, inhibitor

Rucaparib Inhibitor – Cat# MBS5750575

Product References and Citations for Rucaparib, inhibitor

1. Thomas HD,etal.Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial.Mol Cancer Ther. 2007 Mar; 6(3):945-56.

Other Notes

Small volumes of Rucaparib, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rucaparib purchase

MBS5750575 is an inhibitor targeting Rucaparib.
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