Tucidinostat Inhibitor

Name: Tucidinostat Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5750586
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750586

Tucidinostat is an effective and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8/11 (IC50: 733/432 nM), and shows no effect on HDAC4/5/6/7/9. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Tucidinostat, Inhibitor

Full Product Name

Tucidinostat

Product Synonym Names

HDAC inhibitor

Form/Format

POWDER

Purity/Purification

97.00%

Preparation and Storage

Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C

Molecular Weight

390.41

CAS Number

1616493-44-7

Formula

C22H19FN4O2

Smiles

Nc1cc(F)ccc1NC(=O)c1ccc(CNC(=O)\C=C\c2cccnc2)cc1

Solubility

DMSO: 50 mg/mL; Ethanol: 1 mg/mL; Water: Insoluble

Pathways

NF-kappab

Receptor

HDAC1; HDAC2; HDAC3; HDAC10

Product Remark

For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for Tucidinostat, inhibitor

Cancer

Product References and Citations for Tucidinostat, inhibitor

1. Ning ZQ, et al. Chidamide (CS055/HBI-8000): a new histone deacetylase inhibitor of the benzamide class with antitumor activity and the ability to enhance immune cell-mediated tumor cell cytotoxicity. Cancer Chemother Pharmacol. 2012 Apr; 69(4):901-9.

Other Notes

Small volumes of Tucidinostat, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tucidinostat purchase

MBS5750586 is an inhibitor targeting Tucidinostat.