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Bictegravir Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750595

MBS5750595 is an inhibitor targeting Bictegravir. Bictegravir is a potent inhibitor of HIV-1 integrase (IC50: 7.5 nM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Bictegravir, Inhibitor
Full Product Name
Bictegravir
Product Synonym Names
HIV Protease inhibitor
Form/Format
POWDER
Purity/Purification
98.00%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
449.38
CAS Number
1611493-60-7
Formula
C21H18F3N3O5
Smiles
Oc1c2C(=O)N3[C@H]4CC[C@H](C4)O[C@@H]3Cn2cc(C(=O)NCc2c(F)cc(F)cc2F)c1=O
Solubility
DMSO: 80 mg/mL
Pathways
Microbiology & Virology
Receptor
HIV-I integrase
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of Bictegravir, inhibitor

Bictegravir Inhibitor – Cat# MBS5750595

Product References and Citations for Bictegravir, inhibitor

1. Tsiang M, et al. Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile. Antimicrob Agents Chemother. 2016 Nov 21; 60(12):7086-7097.

Other Notes

Small volumes of Bictegravir, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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