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LM22B-10 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750597

LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor and can induce TrkB, TrkC, ERK and AKT activation in vitro and in vivo. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LM22B-10, Inhibitor
Full Product Name
LM22B-10
Product Gene Name
LM22B-10, inhibitor
Product Synonym Names
Trk receptor activator
Form/Format
POWDER
Purity/Purification
98.00%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
485.01
CAS Number
342777-54-2
Formula
C27H33ClN2O4
Smiles
OCCN(CCO)c1ccc(cc1)C(c1ccc(Cl)cc1)c1ccc(cc1)N(CCO)CCO
Solubility
DMSO: 45 mg/mL; Ethanol: 4.5 mg/mL
Pathways
Tyrosine Kinase; Adaptors
Receptor
TrkB; TrkC
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of LM22B-10, inhibitor

LM22B-10 Inhibitor – Cat# MBS5750597

Product References and Citations for LM22B-10, inhibitor

1. Yang T, et al. A small molecule TrkB/TrkC neurotrophin receptor co-activator with distinctive effects on neuronal survival and process outgrowth. Neuropharmacology. 2016 Nov; 110(Pt A):343-61.

Other Notes

Small volumes of LM22B-10, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LM22B-10 purchase

MBS5750597 is an inhibitor targeting LM22B-10.
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