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Talniflumate Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750603

Talniflumate is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3-… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Talniflumate, Inhibitor
Full Product Name
Talniflumate
Product Synonym Names
chloride channel blocker; COX inhibitor; Anion exchanger inhibitor; N-acetylglucosaminyltransferase inhibitor
Form/Format
POWDER
Purity/Purification
98.00%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
414.33
CAS Number
66898-62-2
Formula
C21H13F3N2O4
Smiles
FC(F)(F)c1cccc(Nc2ncccc2C(=O)OC2OC(=O)c3ccccc23)c1
Solubility
DMSO: 10 mg/mL
Pathways
Membrane Transporter; Ion Channel; Immunology; Inflammation; Metabolism
Receptor
hCLCA1/mCLCA3; COX; Cl-/HCO3- exchanger; GCNT3
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of Talniflumate, inhibitor

Talniflumate Inhibitor – Cat# MBS5750603

Product References and Citations for Talniflumate, inhibitor

1. Knight D. Talniflumate (Genaera)[J]. Current Opinion in Investigational Drugs, 2004, 5(5):557-62.

Other Notes

Small volumes of Talniflumate, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Talniflumate purchase

MBS5750603 is an inhibitor targeting Talniflumate.
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