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Tyrphostin AG 528 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750623

Tyrphostin AG 528 is an inhibitor of EGFR (IC50: 4.9 uM) and ErbB2 (IC50: 2.1 uM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tyrphostin AG 528, Inhibitor
Full Product Name
Tyrphostin AG 528
Product Synonym Names
EGFR inhibitor
Form/Format
POWDER
Purity/Purification
98.00%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
306.32
CAS Number
133550-49-9
Formula
C18H14N2O3
Smiles
Oc1ccc(\C=C(/C#N)C(=O)N2CCc3ccccc23)cc1O
Solubility
DMSO: 10 mM
Pathways
Angiogenesis
Receptor
EGFR; ErbB2
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of Tyrphostin AG 528, inhibitor

Tyrphostin AG 528 Inhibitor – Cat# MBS5750623

Product References and Citations for Tyrphostin AG 528, inhibitor

1. Naijue Zhu, et al. Tyrphostin Tumor Growth Inhibitors of EGFR and ErbB2 Tyrosine Kinase. J Chem Crystallogr. 2007, 37, 679-683.

Other Notes

Small volumes of Tyrphostin AG 528, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tyrphostin AG 528 purchase

MBS5750623 is an inhibitor targeting Tyrphostin AG 528.
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