Grazoprevir Inhibitor

Name: Grazoprevir Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5750637
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750637

MK-5172 is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants, with Ki of 0.01 nM (gt1a), 0.08 nM (gt2a), 0.90 nM (gt3a), 0.01 nM (gt1b), 0.15 nM (gt2b), respectively. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Grazoprevir, Inhibitor

Full Product Name

Grazoprevir

Product Synonym Names

Antiviral inhibitor

Form/Format

POWDER

Purity/Purification

98.00%

Preparation and Storage

Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C

Molecular Weight

766.9

CAS Number

1350514-68-9

Formula

C38H50N6O9S

Smiles

COc1ccc2nc3CCCCC[C@@H]4C[C@H]4OC(=O)N[C@H](C(=O)N4C[C@@H](C[C@H]4C(=O)N[C@@]4(C[C@H]4C=C)C(=O)NS(=O)(=O)C4CC4)Oc3nc2c1)C(C)(C)C

Solubility

DMSO: 25 mg/mL; Ethanol: 15 mg/mL

Pathways

Immunology; Inflammation

Receptor

NS3/4a protease

Product Remark

For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for Grazoprevir, inhibitor

Antivirals

Product References and Citations for Grazoprevir, inhibitor

1. Summa V, et al. MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants. Antimicrob Agents Chemother. 2012 Aug; 56(8):4161-7.

Other Notes

Small volumes of Grazoprevir, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Grazoprevir purchase

MBS5750637 is an inhibitor targeting Grazoprevir.