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Ethacrynic Acid Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750651

Ethacrynic acid is a nonsulfonamide loop diuretic that inhibits the activity of the Na+/K+/2Cl- cotransporter NKCC2 in the thick ascending limb of the loop of Henle. It also inhibits glutathione S-transferase and Wnt signalling, producing cytotoxicity in… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ethacrynic Acid, Inhibitor
Full Product Name
Ethacrynic Acid
Product Synonym Names
NKCC inhibitor; GST inhibitor
Form/Format
POWDER
Purity/Purification
98.6%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
303.14
CAS Number
58-54-8
Formula
C13H12Cl2O4
Smiles
CCC(=C)C(=O)c1ccc(OCC(O)=O)c(Cl)c1Cl
Solubility
DMSO: 30 mg/mL; Ethanol: 30 mg/mL
Pathways
Membrane Transporter; Ion Channel
Receptor
NKCC2; GST
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of Ethacrynic Acid, inhibitor

Ethacrynic Acid Inhibitor – Cat# MBS5750651

Product References and Citations for Ethacrynic Acid, inhibitor

1. Kunugi Y, et al. Ethacrynic acid-sensitive and ATP-dependent Cl- transport in the rat kidney[J]. Japanese Journal of Pharmacology, 1991, 57(2):167-74.

Other Notes

Small volumes of Ethacrynic Acid, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ethacrynic Acid purchase

MBS5750651 is an inhibitor targeting Ethacrynic Acid.
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