AHU-377 Inhibitor

Name: AHU-377 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5750661
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750661

AHU-377 is a potent NEP inhibitor with an IC50 of 5 nM. AHU-377 is a component of the heart failure medicine LCZ696. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AHU-377, Inhibitor

Full Product Name

AHU-377

Product Gene Name

AHU-377, inhibitor

Form/Format

POWDER

Purity/Purification

98.00%

Preparation and Storage

Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C

Molecular Weight

411.49

CAS Number

149709-62-6

Formula

C24H29NO5

Smiles

CCOC(=O)[C@H](C)C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)CCC(O)=O

Solubility

DMSO: 10 mM

Receptor

Neprilysin

Product Remark

For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for AHU-377, inhibitor

Cardiovascular Disease

Product References and Citations for AHU-377, inhibitor

1. Ksander GM,etal.Dicarboxylic acid dipeptide neutral endopeptidase inhibitors.J Med Chem. 1995 May 12; 38(10):1689-700.

Other Notes

Small volumes of AHU-377, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AHU-377 purchase

MBS5750661 is an inhibitor targeting AHU-377.