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BMS-5 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750683

BMS-5 is a potent LIMK inhibitor with IC50s of 7 nM and 8 nM for LIMK1 and LIMK2, respectively. More details

Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BMS-5, Inhibitor
Full Product Name
BMS-5
Product Gene Name
Product Synonym Names
LIM Kinase
Form/Format
POWDER
Purity/Purification
98.00%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
431.29
CAS Number
1338247-35-0
Formula
C17H14Cl2F2N4OS
Smiles
O=C(Nc1ncc(s1)c2cc(nn2c3c(Cl)cccc3Cl)C(F)F)C(C)C
Solubility
DMSO: >=34 mg/mL
Pathways
Cell Cycle; Checkpoint
Receptor
LIMK1; LIMK2
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for BMS-5, inhibitor

Product References and Citations for BMS-5, inhibitor

1. Ross-Macdonald P, et al. Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors. Mol Cancer Ther. 2008 Nov; 7(11):3490-8.

Other Notes

Small volumes of BMS-5, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BMS-5 purchase

MBS5750683 is an inhibitor targeting BMS-5.
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