HG-9-91-01 Inhibitor

Name: HG-9-91-01 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5750684
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750684

HG-9-91-01 is a potent and highly selective salt-inducible kinase (SIKs) inhibitor with IC50s of 0.92 nM, 6.6 nM and 9.6 nM for SIK1, SIK2 and SIK3 respectively. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HG-9-91-01, Inhibitor

Full Product Name

HG-9-91-01

Product Gene Name

HG-9-91-01, inhibitor

Product Synonym Names

Salt-inducible Kinase (SIK)

Form/Format

POWDER

Purity/Purification

98.00%

Preparation and Storage

Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C

Molecular Weight

567.68

CAS Number

1456858-58-4

Formula

C32H37N7O3

Smiles

CC1=C(C(=CC=C1)C)NC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC=NC(=C3)NC4=CC=C(C=C4)N5CCN(CC5)C

Solubility

DMSO: >=150 mg/mL; 30% propylene glycol plus 70% ethanol: Soluble

Pathways

Immunology; Inflammation

Receptor

SIK1; SIK2; SIK3

Product Remark

For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for HG-9-91-01, inhibitor

Inflammation/Immunology

Product References and Citations for HG-9-91-01, inhibitor

1. Clark K, et al. Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated andregulatory macrophages. Proc Natl Acad Sci U S A. 2012 Oct 16; 109(42):16986-91.

Other Notes

Small volumes of HG-9-91-01, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HG-9-91-01 purchase

MBS5750684 is an inhibitor targeting HG-9-91-01.