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R-7050 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750713

R-7050 is a tumor necrosis factor receptor (TNFR) antagonist with greater selectivity toward TNFalpha. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
R-7050, Inhibitor
Full Product Name
R-7050
Product Gene Name
R-7050, inhibitor
Product Synonym Names
TNF
Form/Format
POWDER
Purity/Purification
98.00%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
380.77
CAS Number
303997-35-5
Formula
C16H8ClF3N4S
Smiles
FC(F)(F)c3nnc2c(nc1ccc(Cl)cc1n23)Sc4ccccc4
Solubility
DMSO: 25 mg/mL
Pathways
Apoptosis
Receptor
TNF-alpha
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of R-7050, inhibitor

R-7050 Inhibitor – Cat# MBS5750713

Product References and Citations for R-7050, inhibitor

1. Gururaja TL, et al. A class of small molecules that inhibit TNFalpha-induced survival and death pathways viaprevention of interactions between TNFalphaRI, TRADD, and RIP1. Chem Biol. 2007 Oct; 14(10):1105-18.

Other Notes

Small volumes of R-7050, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for R-7050 purchase

MBS5750713 is an inhibitor targeting R-7050.
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