LMI 070 Inhibitor

Name: LMI 070 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5750717
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750717

LMI070 (NVS-SM1) is a highly potent, selective and orally active small molecule SMN2 splicing modulator. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LMI 070, Inhibitor

Full Product Name

LMI 070

Product Gene Name

LMI 070, inhibitor

Product Synonym Names

DNA/RNA Synthesis

Form/Format

POWDER

Purity/Purification

98.00%

Preparation and Storage

Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C

Molecular Weight

393.48

CAS Number

1562338-42-4

Formula

C22H27N5O2

Smiles

CC1(C)CC(CC(C)(C)N1)Oc1ccc(nn1)-c1ccc(cc1O)-c1cn[nH]c1

Solubility

DMSO: 6.12 mg/mL (15.55 mM), Need Ultrasonic and Warming

Pathways

DNA Damage; DNA Repair

Product Remark

For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for LMI 070, inhibitor

Spinal Muscular Atrophy

Product References and Citations for LMI 070, inhibitor

1. Palacino J, et al. SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice. Nat Chem Biol. 2015 Jul; 11(7):511-517.

Other Notes

Small volumes of LMI 070, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LMI 070 purchase

MBS5750717 is an inhibitor targeting LMI 070.