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WHI-P97 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750732

WHI-P97 is a rationally designed potent inhibitor of JAK-3. IC50 value: Target: JAK3 Treatment of mast cells with WHI-P97 inhibited the translocation of 5-lipoxygenase (5-LO) from the nucleoplasm to the nuclear membrane and consequently 5-LO-dependent… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
WHI-P97, Inhibitor
Full Product Name
WHI-P97
Product Gene Name
WHI-P97, inhibitor
Product Synonym Names
JAK
Form/Format
POWDER
Purity/Purification
98.00%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
455.1
CAS Number
211555-05-4
Formula
C16H13Br2N3O3
Smiles
Brc1cc(cc(Br)c1O)Nc3ncnc2cc(OC)c(cc23)OC
Solubility
DMSO: 10 mM
Pathways
Angiogenesis; Chromatin; Epigenetic; Chromatin; Epigenetic; Stem Cells
Receptor
JAK3
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of WHI-P97, inhibitor

WHI-P97 Inhibitor – Cat# MBS5750732

Product References and Citations for WHI-P97, inhibitor

1. Ji KA, Yang MS, Jou I, Shong MH, Joe EH.Thrombin induces expression of cytokine-induced SH2 protein (CIS) in rat brain astrocytes: involvement of phospholipase A2, cyclooxygenase, and lipoxygenase.Glia. 2004 Nov 1; 48(2):102-11.

Other Notes

Small volumes of WHI-P97, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WHI-P97 purchase

MBS5750732 is an inhibitor targeting WHI-P97.
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