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MMAD Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750746

MMAD is a potent tubulin inhibitor, is a toxin payload in antibody drug conjugates (ADCs). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MMAD, Inhibitor
Full Product Name
MMAD
Product Gene Name
MMAD, inhibitor
Product Synonym Names
Microtubule Associated
Form/Format
POWDER
Purity/Purification
98.00%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
771.06
CAS Number
203849-91-6
Formula
C41H66N6O6S
Smiles
O=C(N[C@@H](Cc1ccccc1)c2nccs2)[C@H](C)[C@@H](OC)[C@@H]3CCCN3C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C
Solubility
DMSO: 24.5 mg/mL (31.77 mM), Need Ultrasonic and Warming
Pathways
Cytoskeletal Signaling
Receptor
Microtubule/Tubulin
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of MMAD, inhibitor

MMAD Inhibitor – Cat# MBS5750746

Product References and Citations for MMAD, inhibitor

1. Chudasama V, et al. Recent advances in the construction of antibody-drug conjugates. Nat Chem. 2016 Feb; 8(2):114-9.

Other Notes

Small volumes of MMAD, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MMAD purchase

MBS5750746 is an inhibitor targeting MMAD.
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