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HC-067047 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750749

HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4alpha-PDH. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HC-067047, Inhibitor
Full Product Name
HC-067047
Product Gene Name
HC-067047, inhibitor
Product Synonym Names
TRP/TRPV Channel
Form/Format
POWDER
Purity/Purification
98.00%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
471.51
CAS Number
883031-03-6
Formula
C26H28F3N3O2
Smiles
FC(F)(F)c1cc(ccc1)NC(=O)c4cc(c2ccccc2)n(CCCN3CCOCC3)c4C
Solubility
DMSO: 10 mM
Pathways
Membrane Transporter; Ion Channel
Receptor
hTRPV4/mTRPV4
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of HC-067047, inhibitor

HC-067047 Inhibitor – Cat# MBS5750749

Product References and Citations for HC-067047, inhibitor

1. Everaerts W et al. Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis.Proc Natl Acad Sci U S A. 2010 Nov 2; 107(44):19084-9.

Other Notes

Small volumes of HC-067047, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HC-067047 purchase

MBS5750749 is an inhibitor targeting HC-067047.
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