Palosuran Hydrochloride Inhibitor

Name: Palosuran Hydrochloride Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5750757
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750757

Palosuran is a new potent and specific antagonist of the human UT receptor with an IC50 of 3.6+/-0.2 nM. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Palosuran Hydrochloride, Inhibitor

Full Product Name

Palosuran Hydrochloride 540769-28-6(Free Base)

Product Synonym Names

GPR

Form/Format

POWDER

Purity/Purification

98.00%

Preparation and Storage

Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C

Molecular Weight

454.99

CAS Number

540769-28-6 (Free Base)

Formula

C25H31ClN4O2

Smiles

Cl.Cc1cc(NC(=O)NCCN2CCC(O)(Cc3ccccc3)CC2)c2ccccc2n1

Solubility

DMSO: >30 mg/mL

Pathways

Endocrinology; Hormones

Receptor

Urotensin Receptor (GPR14)

Product Remark

For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for Palosuran Hydrochloride, inhibitor

Cardiovascular System/Metabolism

Product References and Citations for Palosuran Hydrochloride, inhibitor

1. Clozel M, et al. Pharmacology of the urotensin-II receptor antagonist palosuran (ACT-058362; 1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea sulfate salt): first demonstration of a pathophysiological role of the urotensin System.[J]. J Pharmacol Exp Ther, 2004, 311(1):204-212.

Other Notes

Small volumes of Palosuran Hydrochloride, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Palosuran Hydrochloride purchase

MBS5750757 is an inhibitor targeting Palosuran Hydrochloride. Also known as Palosuran Hydrochloride 540769-28-6(Free Base).