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JNJ0966 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750768

MBS5750768 is an inhibitor targeting JNJ0966. JNJ0966 is a highly selective MMP-9 zymogen inhibitor (IC50: 440 nM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
JNJ0966, Inhibitor
Full Product Name
JNJ0966
Product Gene Name
JNJ0966, inhibitor
Product Synonym Names
MMP
Form/Format
POWDER
Purity/Purification
99.46%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
360.45
CAS Number
315705-75-0
Formula
C16H16N4O2S2
Smiles
COc1ccccc1Nc1nc(cs1)-c1sc(NC(C)=O)nc1C
Solubility
DMSO: 150 mg/mL(416.15 mM)
Pathways
Proteases; Proteasome
Receptor
MMP-9
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of JNJ0966, inhibitor

JNJ0966 Inhibitor – Cat# MBS5750768

Product References and Citations for JNJ0966, inhibitor

Scannevin RH, et al. Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) thatallosterically inhibits zymogen activation. J Biol Chem. 2017 Oct 27; 292(43):17963-17974.

Other Notes

Small volumes of JNJ0966, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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