Upadacitinib Inhibitor

Name: Upadacitinib Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751095
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751095

Upadacitinib (ABT-494) is a selective Janus kinase (JAK) 1 inhibitor, which is being studied for the treatment of several autoimmune disorders in the IC50 of 43 nM. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Upadacitinib, Inhibitor

Full Product Name

Upadacitinib

Product Synonym Names

JAK inhibitor

Form/Format

POWDER

Purity/Purification

99.89%

Preparation and Storage

Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C

Molecular Weight

380.37

CAS Number

1310726-60-3

Formula

C17H19F3N6O

Smiles

CC[C@@H]1CN(C[C@@H]1c1cnc2cnc3[nH]ccc3n12)C(=O)NCC(F)(F)F

Solubility

DMSO: >=22 mg/mL

Pathways

JAK; STAT Signaling

Receptor

JAK1; JAK2

Product Remark

For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Product Categories/Family for Upadacitinib, inhibitor

Immunity & Inflammation

Product References and Citations for Upadacitinib, inhibitor

1. Nakayamada S, et al. Recent Progress in JAK Inhibitors for the Treatment of Rheumatoid Arthritis. BioDrugs. 2016 Oct; 30(5):407-419.

Other Notes

Small volumes of Upadacitinib, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Upadacitinib purchase

MBS5751095 is an inhibitor targeting Upadacitinib.