Juglone Inhibitor

Name: Juglone Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751206
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751206

Juglone is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E.… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Juglone, Inhibitor

Full Product Name

Juglone

Product Synonym Names

Regianin; 5-Hydroxy-1,4-naphthoquinone

Form/Format

Powder

Purity/Purification

98.73%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

174.15

Formula

C10H6O3

CAS

481-39-0

Smiles

Oc1cccc2C(=O)C=CC(=O)c12

Receptor (IC50)

RNA polymerase

Solubility

DMSO: 15mg/mL
Ethanol: 15mg/mL
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Juglone, inhibitor

Home; DNA Damage/DNA Repair; DNA/RNA Synthesis

Product References and Citations for Juglone, inhibitor

1. Hennig L, et al. Selective inactivation of parvulin-like peptidyl-prolyl cis/trans isomerases by juglone. Biochemistry. 1998 Apr 28;37 (17):5953-60.
2. Chao SH, et al. Juglone, an inhibitor of the peptidyl-prolyl isomerase Pin1, also directly blocks transcription. Nucleic Acids Res. 2001 Feb 1;29 (3):767-73.
3. Reese S, et al. The Pin 1 inhibitor juglone attenuates kidney fibrogenesis via Pin 1-independent mechanisms in the unilateral ureteral occlusion model. Fibrogenesis Tissue Repair. 2010 Jan 4;3:1.

Other Notes

Small volumes of Juglone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Juglone purchase

MBS5751206 is an inhibitor targeting Juglone.