A939572 Inhibitor

MBS5751213 is an inhibitor targeting A939572. A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4nM for mSCD1 and 37nM for hSCD1.

1. Roongta U V, Pabalan J G, Wang X, et al. Cancer Cell Dependence on Unsaturated Fatty Acids Implicates Stearoyl-CoA Desaturase as a Target for Cancer Therapy[J]. Molecular Cancer Research, 2011, 9 (11):1551-1561.
2. Ben-David U, Gan Q F, Golan-Lev T, et al. Selective Elimination of Human Pluripotent Stem Cells by an Oleate Synthesis Inhibitor Discovered in a High-Throughput Screen[J]. Cell Stem Cell, 2013, 12 (2):167-179.
3. Xin Z, et al. Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors. Bioorg Med Chem Lett. 2008 Aug 1;18 (15):4298-302.

Small volumes of A939572, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.