Neotuberostemonine Inhibitor

Name: Neotuberostemonine Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751423
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751423

Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Neotuberostemonine, Inhibitor

Full Product Name

Neotuberostemonine

Product Synonym Names

Neotuberostemonine(NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour; it has a significant protective effect on bleomycin(BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macrophages. Neotuberostemonine demonstrates antitussive properties in guinea pigs.

Form/Format

Powder

Purity/Purification

99.73%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

375.5

Formula

C22H33NO4

CAS

143120-46-1

Smiles

CC[C@H]1[C@H]2OC(=O)[C@@H](C)[C@H]2[C@@H]2C[C@@H]([C@@H]3C[C@H](C)C(=O)O3)N3CCCC[C@H]1[C@H]23

Solubility

DMSO: 10mM
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Neotuberostemonine, inhibitor

Home; Immunology/Inflammation; NOS

Product References and Citations for Neotuberostemonine, inhibitor

1. Xiang J, Cheng S, Feng T, et al. Neotuberostemonine attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages[J]. International Immunopharmacology, 2016, 36:158-164.
2. Gritsanapan W. TLC-image analysis of non-chromophoric tuberostemonine alkaloid derivatives in stemona species[J]. Natural Product Communications, 2013, 8 (8):1065-1068.
3. Xu Y T, Shaw P C, Jiang R W, et al. Antitussive and central respiratory depressant effects of Stemona tuberosa[J]. Journal of Ethnopharmacology, 2010, 128 (3):0-684.

Other Notes

Small volumes of Neotuberostemonine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Neotuberostemonine purchase

MBS5751423 is an inhibitor targeting Neotuberostemonine.