Brequinar Inhibitor

Name: Brequinar Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751487
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751487

Brequinar is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Brequinar, Inhibitor

Full Product Name

Brequinar

Product Synonym Names

NSC 368390; DUP785; Bipenquinate

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

375.37

Formula

C22H13F2NO2

CAS

96187-53-0

Smiles

Cc1c(nc2ccc(F)cc2c1C(O)=O)-c1ccc(cc1)-c1ccccc1F

Solubility

DMSO: >= 62.5mg/mL (166.50mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Brequinar, inhibitor

Home; Others

Product References and Citations for Brequinar, inhibitor

1. Qing M, et al. Characterization of dengue virus resistance to brequinar in cell culture. Antimicrob Agents Chemother. 2010 Sep;54 (9):3686-95.
2. Schnellrath LC, et al. Potent antiviral activity of brequinar against the emerging Cantagalo virus in cell culture. Int J Antimicrob Agents. 2011 Nov;38 (5):435-41.
3. Xu X, et al. In vitro and in vivo mechanisms of action of the antiproliferative and immunosuppressive agent, brequinar sodium. J Immunol. 1998 Jan 15;160 (2):846-53.

Other Notes

Small volumes of Brequinar, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Brequinar purchase

MBS5751487 is an inhibitor targeting Brequinar.