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Orotic Acid Monohydrate Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751541

MBS5751541 is an inhibitor targeting Orotic Acid Monohydrate. Orotic acid is an intermediate product in pyrimidine metabolism. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Orotic Acid Monohydrate, Inhibitor
Full Product Name
Orotic Acid Monohydrate
Product Synonym Names
2,4-dioxo-1H-pyrimidine-6-carboxylic acid hydrate
Form/Format
Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
174.11
Formula
C5H6N2O5
CAS
50887-69-9
Smiles
O.OC(=O)c1cc(=O)[nH]c(=O)[nH]1
Solubility
DMSO: 2mg/mL (12.81mM)
Ethanol: <1mg/mL
Water: <1mg/mL
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Orotic Acid Monohydrate, inhibitor

Home; Others

Structure of Orotic Acid Monohydrate, inhibitor

Orotic Acid Monohydrate Inhibitor – Cat# MBS5751541

Product References and Citations for Orotic Acid Monohydrate, inhibitor

1. Jung, E.J., et al, Proliferating effect of orotic acid through mTORC1 activation mediated by negative regulation of AMPK in SK-Hep1 hepatocellular carcinoma cells. J Toxicol Sci, 2012. 37 (4): p. 813-21.
2. Manjeshwar, S., et al., The regulation of ribonucleoside diphosphate reductase by the tumor promoter orotic acid in normal rat liver in vivo. Mol Carcinog, 1999. 24 (3): p. 188-96.
3. Jung, E.J., et al., Role of the AMPK/SREBP-1 pathway in the development of orotic acid-induced fatty liver. J Lipid Res, 2011. 52 (9): p. 1617-25.

Other Notes

Small volumes of Orotic Acid Monohydrate, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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